|
KMID : 1024420140180040359
|
|
Food Engineering Progress
2014 Volume.18 No. 4 p.359 ~ p.365
|
|
|
Antioxidative and Anticancer Activities of the Betatini Cultivar of Cherry Tomato (Lycopersicon esculentum var. cerasiforme) Extract
|
|
Kim Hyen-Ryung
Ahn Jun-Bae
|
|
|
Abstract
|
|
|
|
The aim of this study is to investigate the effectiveness of a cherry tomato (Betatini cultivar) as a functional foodand food material by measuring total polyphenol and flavonoid content, antioxidative and anticancer activities. Thecontents of polyphenols and flavonoids were 11.02±1.98 mg and 4.53±0.59 mg per gram of dried cherry tomato,respectively. The antioxidative activity of the cherry tomato extract was verified by measuring α-α-Diphenyl-β-pic-rylhydrazyl (DPPH) radical scavenging activity (DSA), 2,2’-azinobis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS)radical scavenging activity (ASA) and ferric reducing antioxidant power (FRAP). Half of the radical scavengingconcentrations (IC50) of DSA and ASA were 340.26±4.28μg/mL and 350.77±7.79μg/mL, respectively. The FRAPvalue was 25.47±0.79μmol Fe2+/g. The effects of the cherry tomato extract on the growth of normal liver cell(Chang), normal lung cell (Hel299), lung cancer cell (A549), cervical cancer cell (HeLa) and liver cancer cell(HepG2) were also investigated using MTT assay. The cherry tomato extract showed high growth inhibition effectsagainst HeLa and HepG2 cell. These results indicate that the Betatini cultivar of cherry tomato would be a func-tional food and food material.
|
|
|
KEYWORD
|
|
|
cherry tomato, Betatini cultivar, DPPH, ABTS, FRAP, anticancer, MTT assay
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|